JTV-803 mesylate - CAS 247131-79-9

JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K (i) value of 0.019 microM and IC (50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting human factor Xa as compared to its inhibitory activity against thrombin, trypsin and plasmin. JTV-803 prolonged activated partial thromboplastin time and prothrombin time in a dose-dependent manner.

Endogenous Metabolite, Others

Others, Metabolism

247043

C23H31N5O6S

505.59

O=C(O)C1(COC2=CC=C3C(=C2)CN(C(=N)N)CC3)CCN(C=4C=CN=CC4)CC1.O=S(=O)(O)C

-20°C

Ice Packs

Small Compound