JZP-MA-11 - CAS 1672691-50-7

JZP-MA-11 is a positron emission tomography (PET) ligand that specifically targets the endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. It exhibits selective inhibition of ABHD6 with an IC50 value of 126 nM and can cross the blood-brain barrier (BBB) . The compound, labeled with [18F], shows promising potential for preclinical evaluation in mice and nonhuman primates (NHP) as a tool for investigating brain ABHD6 activity [1].

Others, MAGL

Others, Metabolism

1672634

C15H17FN4O2S

336.38

CN(C(=O)Oc1nsnc1N1CCCCC1)c1ccc(F)cc1

-20°C

Ice Packs

Small Compound