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K-756 - CAS 130017-40-2
K-756 - CAS 130017-40-2
SKU:MF-0033094-01
Regular price
$42.89 USD
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$42.89 USD
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Product Details
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Bioactivity
K-756 is a direct and selective inhibitor of tankyrase (TNKS), inhibiting the ADP-ribosylation activity of TNKS1 [IC50 = 31 nM] and TNKS2 [IC50 = 36 nM].
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Target
PARP, Wnt/beta-catenin
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Related Pathways
Chromatin/Epigenetic, Stem Cells, DNA Damage/DNA Repair, Cytoskeletal Signaling
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CAS Number
129975
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Purity
0.9981
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Molecular Formula
C24H27N5O3
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Molecular Weight
433.5
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SMILES
COc1cc2ncnc(N3CCC(CN4Cc5ccccc5NC4=O)CC3)c2cc1OC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound