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K-Ras-IN-3 - CAS 3024991-82-7
K-Ras-IN-3 - CAS 3024991-82-7
SKU:MF-0122080-01
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Product Details
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Bioactivity
K-Ras-IN-3 (compound 3) is an effective inhibitor of GDP-KRAS G12V, exhibiting an IC50 value of 0.371 nM. It has potential for use in cancer research.
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Target
Ras, Kras
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Related Pathways
MAPK
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CAS Number
3024991-82-7
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Molecular Formula
C34H29F6N5O4
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Molecular Weight
685.62
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SMILES
C(C(O)=O)(F)(F)F.C(OC1=NC2=C(C(N(C)[C@@H]3[C@@H](F)C3)=N1)C=NC(=C2F)C=4C5=C(C=C(O)C4)C=CC(F)=C5C#C)C67N(CC(=C)C6)CCC7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound