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Molfinity

K145 - CAS 1309444-75-4

K145 - CAS 1309444-75-4

MF-0022685-01

$1,515.42 USD
$1,515.42 USD
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Product Details

  • Bioactivity

    K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity. K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM.

  • Target

    Others, Apoptosis, S1P Receptor

  • Related Pathways

    Others, Apoptosis, GPCR/G Protein

  • CAS Number

    1309365

  • Molecular Formula

    C18H24N2O3S

  • Molecular Weight

    348.46

  • SMILES

    C(CN)N1C(=O)C(=CCCC2=CC=C(OCCCC)C=C2)SC1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound