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Molfinity

K41498 - CAS 434938-41-7

K41498 - CAS 434938-41-7

MF-0096181

$1,778.67 USD
$1,778.67 USD
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Product Details

  • Bioactivity

    Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively) . Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. In rats in vivo, blocks urocortin-induced hypotension following systemic administration.

  • Target

    CRFR

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    434890

  • Molecular Formula

    C162H276N48O46

  • Molecular Weight

    3632.26

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide