K811 - CAS 1355228-38-4

K811 is an ASK1-specific inhibitor that prolongs survival in a mouse model of amyotrophic lateral sclerosis. K811 efficiently prevented cell proliferation in cell lines with high ASK1 expression and in HER2-overexpressing GC cells. Treatment with K811 reduced sizes of xenograft tumors by downregulating proliferation markers.

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Others

1355186

C29H26N4O5

510.54

C(C)(C)N1C=2C(C(=O)C(C(NC3=CC=C(OC=4C5=C(C=C(OC)C(OC)=C5)N=NC4)C=C3)=O)=C1)=CC=CC2

-20°C

Ice Packs

Small Compound