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Kaempferitrin - CAS 482-38-2

Kaempferitrin - CAS 482-38-2

SKU:MF-0093823-01

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  • Bioactivity

    Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucose-metabolizing enzymes, promotes glucose homeostasis. Kaempferitrin exerts immunostimulatory effects on immune responses mediated by splenocytes, macrophages, PBMC and NK cells. Kaempferitrin induces cytotoxic effects to include: cell cycle arrest in G1 phase and apoptosis via the intrinsic pathway in a caspase-dependent pathway.

  • Target

    Cell Cycle Arrest, Glucokinase, IGF-1R

  • Related Pathways

    Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Metabolism

  • CAS Number

    442

  • Purity

    0.9959

  • Molecular Formula

    C27H30O14

  • Molecular Weight

    578.52

  • SMILES

    C[C@@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(-c2ccc(O)cc2)c(O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)c3=O)[C@H](O)[C@H](O)[C@H]1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product