Kamebakaurin - CAS 73981-34-7

1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity. 3. Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50.4. Kamebakaurin has anti-neuroinflammatory activity via inhibition of c-Jun NH -terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells.

NF-κB, Caspase, Apoptosis, HIF/HIF Prolyl-Hydroxylase

NF-κB, Proteases/Proteasome, Metabolism, Apoptosis, Chromatin/Epigenetic

73940

0.9805

C20H30O5

350.45

[H][C@@]1(O)[C@H]2CC[C@]3([H])[C@]1([C@H](O)C[C@]1([H])C(C)CC[C@H](O)[C@@]31CO)C(=O)C2=C

-20°C

Ice Packs

Natural Product