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Molfinity

KARI 201 - CAS 2376132-22-6

KARI 201 - CAS 2376132-22-6

SKU:MF-0117852-01

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  • Bioactivity

    KARI 201 is a selective, brain-penetrant, competitive inhibitor of acid sphingomyelinase (ASM) with an IC50 of 338.3 nM. Additionally, KARI 201 acts as an agonist of the growth hormone secretagogue receptor (ghrelin receptor) . It is capable of improving the neuropathological characteristics of Alzheimer's disease.

  • Target

    Phospholipase, GHSR

  • Related Pathways

    Metabolism, GPCR/G Protein

  • CAS Number

    2376104

  • Molecular Formula

    C14H28N4O2

  • Molecular Weight

    284.4

  • SMILES

    OCC(N)(C=1N=NN(C1)CCCCCCCCC)CO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound