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KARI 201 - CAS 2376132-22-6
KARI 201 - CAS 2376132-22-6
SKU:MF-0117852-01
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Product Details
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Bioactivity
KARI 201 is a selective, brain-penetrant, competitive inhibitor of acid sphingomyelinase (ASM) with an IC50 of 338.3 nM. Additionally, KARI 201 acts as an agonist of the growth hormone secretagogue receptor (ghrelin receptor) . It is capable of improving the neuropathological characteristics of Alzheimer's disease.
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Target
Phospholipase, GHSR
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Related Pathways
Metabolism, GPCR/G Protein
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CAS Number
2376104
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Molecular Formula
C14H28N4O2
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Molecular Weight
284.4
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SMILES
OCC(N)(C=1N=NN(C1)CCCCCCCCC)CO
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound