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KARI 201 hydrochloride - CAS 2376132-24-8

KARI 201 hydrochloride - CAS 2376132-24-8

MF-0118144-01

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Product Details

  • Bioactivity

    KARI 201 hydrochloride is a selective, brain-penetrant, competitive inhibitor of acid sphingomyelinase (ASM) with an IC50 of 338.3 nM. It also acts as an agonist for the growth hormone-releasing peptide receptor (ghrelin receptor) . Additionally, KARI 201 hydrochloride can enhance the neuropathological features of Alzheimer's disease.

  • Target

    GHSR, Phospholipase

  • Related Pathways

    GPCR/G Protein, Metabolism

  • CAS Number

    2376100

  • Molecular Formula

    C14H29ClN4O2

  • Molecular Weight

    320.86

  • SMILES

    Cl.OCC(N)(C=1N=NN(C1)CCCCCCCCC)CO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound