KB-R7785 - CAS 168158-16-5

KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) model by inhibiting the proteolytic activation of HB-EGF signaling, exerting its antidiabetic effect by ameliorating insulin sensitivity through the inhibition of TNF-alpha production.

Others, MMP

Proteases/Proteasome, Others

168137

C18H27N3O4

349.42

[C@@H](NC([C@@H]([C@@H](C(NO)=O)C)CC(C)C)=O)(C(NC)=O)C1=CC=CC=C1

-20°C

Ice Packs

Small Compound