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KDM2/7-IN-1 - CAS 1453071-47-0

KDM2/7-IN-1 - CAS 1453071-47-0

SKU:MF-0050617-01

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  • Bioactivity

    KDM2/7-IN-1 (TC-E 5002) is a selective small-molecule inhibitor of the KDM2/7 histone demethylase subfamily, exhibiting IC50 values of 0.2, 1.2, 6.8, 55, 83, >100, and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A, and KDM4A, respectively. KDM2/7-IN-1 inhibits the proliferation of HeLa and KYSE-150 cancer cells in vitro, highlighting its utility in epigenetic and oncology research.

  • Target

    Histone Demethylase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    1453024

  • Purity

    0.9987

  • Molecular Formula

    C15H27NO4

  • Molecular Weight

    285.38

  • SMILES

    O=C(O)CCN(O)C(=O)CCCCCCCCC1CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound