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KDM2/7-IN-1 - CAS 1453071-47-0
KDM2/7-IN-1 - CAS 1453071-47-0
SKU:MF-0050617-01
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Product Details
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Bioactivity
KDM2/7-IN-1 (TC-E 5002) is a selective small-molecule inhibitor of the KDM2/7 histone demethylase subfamily, exhibiting IC50 values of 0.2, 1.2, 6.8, 55, 83, >100, and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A, and KDM4A, respectively. KDM2/7-IN-1 inhibits the proliferation of HeLa and KYSE-150 cancer cells in vitro, highlighting its utility in epigenetic and oncology research.
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Target
Histone Demethylase
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Related Pathways
Chromatin/Epigenetic
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CAS Number
1453024
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Purity
0.9987
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Molecular Formula
C15H27NO4
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Molecular Weight
285.38
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SMILES
O=C(O)CCN(O)C(=O)CCCCCCCCC1CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound