KDM4-IN-4 - CAS 2230475-63-3

KDM4-IN-4 (compound 47) is a potent inhibitor of histone lysine demethylase 4 (KDM4), with a binding constant of approximately 80 μM for the KDM4A-Tudor domain. It inhibits H3K4Me3 binding to the Tudor domain in cellular contexts with an EC50 value of 105 μM, holding potential for anticancer research applications [1].

Histone Demethylase

Chromatin/Epigenetic

2230409

0.9961

C16H23NO

245.36

O[C@@H]1[C@]2(C[C@@]([C@@H]1CN(C)C)(CC2)[H])C3=CC=CC=C3

-20°C

Ice Packs

Small Compound