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Keap1-Nrf2-IN-10 - CAS 2445349-54-0
Keap1-Nrf2-IN-10 - CAS 2445349-54-0
SKU:MF-0159217-01
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Product Details
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Bioactivity
Keap1-Nrf2-IN-10 (compound 15) is a potent inducer of NQO1 that effectively mitigates oxidative stress in gamma-irradiated mice by reducing MDA and ROS levels, and NQO1 in the liver, thereby enhancing survival rates [1].
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Target
Others, Reactive Oxygen Species
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Related Pathways
Others, Metabolism, NF-κB, Immunology/Inflammation
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CAS Number
2445349-54-0
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Molecular Formula
C25H22I2N4O7S2
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Molecular Weight
808.4
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SMILES
O=C1C=2C=C(I)C=C(I)C2N=C(SCC(=O)NC3=CC(OC)=C(OC)C(OC)=C3)N1C4=CC=C(C=C4)S(=O)(=O)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound