Keap1-Nrf2-IN-15 - CAS 2456295-45-5

Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, with IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1].

Nrf2, Others

Others, Immunology/Inflammation

2456245

C39H35N3O12S2

801.84

N(S(=O)(=O)C1=CC=C(OC)C=C1)(CC(O)=O)C=2C3=C(C(N(S(=O)(=O)C4=CC=C(OC)C=C4)CC(O)=O)=CC2CCCN5C(=O)C=6C(C5=O)=CC=CC6)C=CC=C3

-20°C

Ice Packs

Small Compound