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Keap1-Nrf2-IN-23 - CAS 2771115-65-0

Keap1-Nrf2-IN-23 - CAS 2771115-65-0

MF-0142762-01

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Product Details

  • Bioactivity

    Keap1-Nrf2-IN-23 (compound 56) acts as an inhibitor of the Keap1–Nrf2 PPI (IC50=16.0 nM) . It exhibits a Kd value of 3.07 nM when binding to Keap1 and demonstrates oral activity.

  • Target

    Nrf2

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2771050

  • Molecular Formula

    C30H31ClN4O5

  • Molecular Weight

    563.04

  • SMILES

    O=C(O)CC(C1=CC=2N=NN(C2C(OC)=C1)C)C=3C=CC=C4C3CCN(C(=O)C5=CC=C(OC(C)C)C=C5Cl)C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound