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Keap1-Nrf2-IN-28 - CAS 3075750-60-3

Keap1-Nrf2-IN-28 - CAS 3075750-60-3

MF-0115063-01

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Product Details

  • Bioactivity

    Keap1-Nrf2-IN-28 (SG16) is an orally active inhibitor of Keap1-Nrf2. It demonstrates antioxidant properties and upregulates the expression of Nrf2, HO-1, GCLM, and Akr1c1. Additionally, Keap1-Nrf2-IN-28 can mitigate acute liver injury induced by APAP.

  • Target

    Nrf2

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    3075687

  • Molecular Formula

    C22H16FNO5S

  • Molecular Weight

    425.43

  • SMILES

    O=C1C=C(OC2=CC(=CC=C12)NS(=O)(=O)C3=CC=C(F)C=C3)C=4C=CC(OC)=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound