KG-548 - CAS 175205-09-1

KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, binding to the β-fold surface involved in HIF-2 dimerization and coactivator recruitment, inhibiting lactate production and useful in cancer research.

HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, HIF

Cytoskeletal Signaling, Metabolism, Chromatin/Epigenetic, Angiogenesis

175205-09-1

0.9962

C9H4F6N4

282.15

FC(F)(F)C1=CC(=CC(=C1)C(F)(F)F)C2=NN=NN2

-20°C

Ice Packs

Small Compound