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Molfinity

KG5 - CAS 877874-85-6

KG5 - CAS 877874-85-6

MF-0016302-01

$31.68 USD
$31.68 USD
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Product Details

  • Bioactivity

    KG5 is a dual allosteric inhibitor of PDGFRβ and B-Raf with a Kd of 520 nM and 300 nM for PDGFRβ and PDGFRα. KG5 inhibits FLT3, KIT, and c-Raf with anticancer and antiangiogenic activities.

  • Target

    PDGFR, c-Kit, FLT, Raf

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, MAPK

  • CAS Number

    877783

  • Purity

    0.9832

  • Molecular Formula

    C20H16F3N7OS

  • Molecular Weight

    459.45

  • SMILES

    CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound