KH-176M - CAS 2095304-61-1

KH176m serves as a selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), effectively suppressing mPGES-1 expression. It inhibits the growth of DU145-derived spheroids, but does not affect cells with low mPGES-1 expression such as LNCaP. As an antioxidant and redox modulator, KH176m demonstrates high efficacy in combating cardiac oxidative stress, with its impact varying according to the duration of ischemia. It holds potential therapeutic value in alleviating acute cardiac ischemia-reperfusion injury (IRI) .

2095242

C19H28N2O4

348.44

C(C[C@](C(N[C@@H]1CCCNC1)=O)(C)O)C2=C(C)C(=O)C(C)=C(C)C2=O

-20°C

Ice Packs

Small Compound