KI-CDK9d-32 - CAS 3054009-82-1

KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.

C-Myc, PROTACs, CDK

Cell Cycle/Checkpoint, PROTAC

3053926

C39H45N9O4

703.83

O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)N4CCN(CC5=CC=C(C(N[C@H]6C[C@H](NC=7N8C(N=C(CCC)C7)=CC=N8)CC6)=O)C=C5)CC4

-20°C

Ice Packs

PROTAC