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KIF18A-IN-10 - CAS 3034542-28-1
KIF18A-IN-10 - CAS 3034542-28-1
SKU:MF-0121776-01
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Product Details
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Bioactivity
KIF18A-IN-10 (Compound 24) is a potent inhibitor of KIF18A with an IC50 value of 3.8 nM. It exhibits anticancer activity with IC50 values below 100 nM in OVCAR3 and MDA-MB-157 cells.
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Target
Microtubule Associated, Kinesin
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Related Pathways
Cytoskeletal Signaling
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CAS Number
3034542-28-1
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Molecular Formula
C26H30F2N6O4S
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Molecular Weight
560.62
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SMILES
O=C(NC1=NC2=C(C=NN2C3CC(F)(F)C3)C=C1)C4=CC=C(C=C4N5CCC6(CC5)CC6)NS(=O)(=O)CCO
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound