KIF18A-IN-14 - CAS 3051552-75-8

KIF18A-IN-14 (Compound Example 81) is an inhibitor of KIF18A that exists in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit the viability of OVCAR-3 cells with IC50 values of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be utilized in tumor research, including studies on colon cancer, breast cancer, and lung cancer.

Kinesin

Cytoskeletal Signaling

3051469

C26H32F3N5O6S

599.62

O=C1NC=2N=C(C=CC2)N3CCOC(COCC4(CCN(C5=CC(=CC=C15)NS(=O)(=O)CCO)CC4)C(F)(F)F)C3

-20°C

Ice Packs

Small Compound