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KIF18A-IN-15 - CAS 3051552-64-5

KIF18A-IN-15 - CAS 3051552-64-5

SKU:MF-0112220-01

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  • Bioactivity

    KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.

  • Target

    Kinesin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    3051483

  • Molecular Formula

    C25H33F3N6O5S

  • Molecular Weight

    586.63

  • SMILES

    O=C1NC2=CC(=NC(=NCC(C)COCC3(CCN(C4=CC(=CC=C14)NS(=O)(=O)CCO)CC3)C(F)(F)F)N2)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound