KIF18A-IN-4 - CAS 1197522-21-6

KIF18A-IN-4 is a moderately potent, non-competitive KIF18A inhibitor of ATP and microtubule with an IC50 of 6.16 μM. It selectively acts on many mitotic kinesins and kinases, without directly affecting microtubule protein assembly, and shows anti-tumour effects.

Kinesin, Others, Microtubule Associated

Others, Cytoskeletal Signaling

1197495

C22H27N3O3S

413.53

C(NC1=CC(S(=O)(=O)C2CCCC2)=CC=C1)(=O)C3=C(N=CC=C3)N4CCCCC4

-20°C

Ice Packs

Small Compound