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KIF18A-IN-6 - CAS 2914879-10-8

KIF18A-IN-6 - CAS 2914879-10-8

MF-0095326-01

$59.34 USD
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Product Details

  • Bioactivity

    KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor that suppresses KIF18A microtubule-dependent ATPase activity with an IC50 of 0.016 μM. It reduces HCC15 tumour volume in mouse models and may be employed in KIF18A-associated cancer research.

  • Target

    Kinesin, Microtubule Associated

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    2914861

  • Purity

    0.9759

  • Molecular Formula

    C28H37N3O5S2

  • Molecular Weight

    559.74

  • SMILES

    O=C(C1=CC=CC(=C1)S(=O)(=O)NC(C)(C)C)N2C3=CC=C(C=C3C4(C2)CCC5(CC4)CC5)NS(=O)(=O)CC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound