KL 465 - CAS 3057446-82-6

KL 465 is a degrader of MAGE-A3. The degradation of MAGE-A3 caused by KL 465 leads to reduced viability of cancer cells, and this effect is dependent on the VHL protein.

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Others

3057358

C56H60N8O9S

1021.19

C(C=1C=C(C2=C3C(=CC=C2)NN=C3)C=CC1OCCOCCOC4=C(CNC(=O)[C@H]5N(C([C@H](C(C)C)N6C(=O)C=7C(C6)=CC=CC7)=O)C[C@H](O)C5)C=CC(=C4)C8=C(C)N=CS8)N9CCN(C(=O)C%10=CC=CO%10)CC9

-20°C

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