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KLHDC2-IN-1 - CAS 1005275-19-3

KLHDC2-IN-1 - CAS 1005275-19-3

MF-0118414-01

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Product Details

  • Bioactivity

    KLHDC2-IN-1 (Compound 6) is a ligand that specifically targets the ubiquitin E3 ligase KLHDC2 with a dissociation constant (Kd) of 160 nM. It can be synthesized into a PROTAC capable of effectively degrading BRD4 within cells.

  • Target

    Ligand for E3 Ligase

  • Related Pathways

    PROTAC

  • CAS Number

    1005253

  • Molecular Formula

    C22H19ClF3NO3

  • Molecular Weight

    437.84

  • SMILES

    O=C(O)C1=CC(Cl)=CC2=C1NC(C=3C=CC=C(OC(F)(F)F)C3)C4C2C5CCC4C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC