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Molfinity

KML29 - CAS 1380424-42-9

KML29 - CAS 1380424-42-9

MF-0014302-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM) . It has not inhibitory for FAAH (IC50 > 50 μM) . It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 μM, AEA) .

  • Target

    Lipase, MAGL

  • Related Pathways

    Metabolism

  • CAS Number

    1380373

  • Purity

    0.9865

  • Molecular Formula

    C24H21F6NO7

  • Molecular Weight

    549.42

  • SMILES

    OC(C1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)(c1ccc2OCOc2c1)c1ccc2OCOc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound