KMS99220 - CAS 1478585-60-2

KMS99220 is an orally active Keap-1 activator that acts as an Nrf2 inhibitor protein. It enhances Nrf2 nuclear translocation, increases the expression of antioxidant enzymes (such as heme oxygenase-1) and proteasome subunit genes, and alleviates oxidative stress and protein aggregation damage. KMS99220 is applicable for research in Parkinson's disease (PD) .

Nrf2

Immunology/Inflammation

1478523

C23H25ClF3NO3

455.9

C(=C/C(=O)C1=CC=C(OCCCN2CCOCC2)C=C1)\C3=C(C(F)(F)F)C=CC=C3.Cl

-20°C

Ice Packs

Small Compound