Kobophenol A - CAS 124027-58-3

Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-dependent manner, and the IC50 value is 115.8mM. Kobophenol A has protective effect against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells.

PKC, ROS, DNA/RNA Synthesis, p38 MAPK, Bcl-2 Family, NF-κB, MMP, SARS-CoV, JNK, CDK

Cell Cycle/Checkpoint, Microbiology/Virology, Cytoskeletal Signaling, MAPK, Apoptosis, Proteases/Proteasome, Chromatin/Epigenetic, NF-κB, Immunology/Inflammation, DNA Damage/DNA Repair

124027-58-3

C56H44O13

924.94

Oc1ccc(cc1)[C@H]1O[C@@H]([C@@H]([C@@H]1c1cc(O)cc(O)c1)c1cc(O)cc2O[C@@H]([C@H](c12)c1cc(O)cc2O[C@H]([C@@H](c12)c1cc(O)cc(O)c1)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1

-20°C

Ice Packs

Natural Product