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KPZ560 - CAS 2397562-43-3
KPZ560 - CAS 2397562-43-3
SKU:MF-0159208-01
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Product Details
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Bioactivity
KPZ560, a potent HDAC 1 and HDAC 2 inhibitor, exhibits IC50 values of 12 nM and 68 nM, respectively. This compound enhances spine density in mouse granule neuron dendrites and inhibits growth in the MCF-7 breast cancer cell line [1].
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Target
HDAC
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Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
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CAS Number
2397562-43-3
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Molecular Formula
C26H21N5O3S2
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Molecular Weight
515.61
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SMILES
O=C(NC=1C=C(C=CC1N)C=2SC=CC2)C=3C=CC(=CC3)C=4N=NN(C4)CS(=O)(=O)C=5C=CC=CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound