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Molfinity

KR-32568 - CAS 852146-73-7

KR-32568 - CAS 852146-73-7

SKU:MF-0013331-01

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  • Bioactivity

    KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM) with potent cardioprotective effects. At a concentration of 10 μM, it restored cardiac systolic function in an isolated ischemic rat heart model. Additionally, KR-32568 (0.3 mg/kg) reduced myocardial infarction size in a rat model of ischemia and reperfusion injury.

  • Target

    Sodium Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    852066

  • Purity

    0.9991

  • Molecular Formula

    C13H12FN3O2

  • Molecular Weight

    261.25

  • SMILES

    CC1=C(C=2OC(C(NC(=N)N)=O)=CC2)C=C(F)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound