KR-39038 - CAS 2770300-35-9

KR-39038 is an orally active GRK5 (G protein-coupled receptor kinase 5) inhibitor (IC50: 0.02 μM) that inhibits the HDAC5 pathway in neonatal cardiomyocytes and significantly reduces angiotensin II-induced hypertrophy, leading to notable anti-myocardial hypertrophy effects and improved cardiac function. KR-39038 is applicable for heart failure research.

Others, GRK, HDAC

Chromatin/Epigenetic, Others, DNA Damage/DNA Repair, GPCR/G Protein

2770256

C24H32ClFN6O

475

O=C1N=C(NC2=CC(NCCCNCCCCNCCCN)=C(F)C=C12)C=3C=CC=CC3Cl

-20°C

Ice Packs

Small Compound