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KR31173 - CAS 260554-07-2
KR31173 - CAS 260554-07-2
SKU:MF-0115050-01
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Product Details
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Bioactivity
KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET) . In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.
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Target
RAAS
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Related Pathways
Endocrinology/Hormones
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CAS Number
260554-07-2
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Molecular Formula
C31H30N8O2
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Molecular Weight
546.62
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SMILES
COCC1=NC2=C(N=C(CCCC)N2CC3=CC=C(C4=C(C5=NN=NN5)C=CC=C4)C=C3)C=C1C6=[N+]([O-])C=CC=C6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound