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KRA-533 - CAS 10161-87-2
KRA-533 - CAS 10161-87-2
SKU:MF-0011870-01
Regular price
$34.67 USD
Regular price
$21.45 USD
Sale price
$34.67 USD
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Product Details
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Bioactivity
KRA-533 is an effective KRAS agonist that targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage. This leads to accumulation of the active GTP-KRAS form, promoting apoptosis and autophagic death in cancer cells.
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Target
Kras, Autophagy, Ras, Apoptosis
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Related Pathways
MAPK, Apoptosis, Autophagy
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CAS Number
10161-87-2
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Purity
0.9811
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Molecular Formula
C13H16BrNO3
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Molecular Weight
314.18
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SMILES
OC(=O)c1ccc(CCCCNC(=O)CBr)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound