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KRAS G12C-IN-70 - CAS 2923865-76-1
KRAS G12C-IN-70 - CAS 2923865-76-1
SKU:MF-0117864-01
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Product Details
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Bioactivity
KRAS G12C-IN-70 is a selective inhibitor targeting the KRAS G12C mutant. It disrupts downstream signaling pathways mediated by KRAS G12C, such as RAF-MEK-ERK, thereby inhibiting tumor cell proliferation. KRAS G12C-IN-70 is a promising candidate for research related to tumors associated with KRAS G12C mutations, including non-small cell lung cancer and colorectal cancer.
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Target
Ras
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Related Pathways
MAPK
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CAS Number
2923788
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Molecular Formula
C26H19ClF2N6O2S
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Molecular Weight
552.98
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SMILES
ClC=1C2=C3C(C(=O)N4[C@](CCN3N1)(CN(C(C=C)=O)CC4)[H])=CC(F)=C2C5=C6C(SC(N)=C6C#N)=C(F)C=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound