KRAS G12D-IN-29 - CAS 3018057-89-8

KRAS G12D inhibitor 29 (Compound Formula (I) ) is an orally active and selective inhibitor of KRASG12D. It effectively blocks KRASG12D-mediated downstream signaling pathways, thereby inhibiting the proliferation of tumor cells. This compound holds potential for research into cancers associated with KRASG12D mutations, such as pancreatic cancer, lung cancer, and colorectal cancer.

Ras

MAPK

3017960

C31H33F6N7O2

649.63

FC=1C2=C3C(N4[C@]([C@H](C)OC3=NC1C5=C(C(F)(F)F)C(C)=C(F)C(N)=C5)([C@]6(N[C@@](C4)(CC6)[H])[H])[H])=NC(OC[C@@]78N(C[C@H](F)C7)CCC8)=N2

-20°C

Ice Packs

Small Compound