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KRAS G12D inhibitor 1 - CAS 2621928-43-4

KRAS G12D inhibitor 1 - CAS 2621928-43-4

MF-0153225

$11,018.75 USD
$11,018.75 USD
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Product Details

  • Bioactivity

    KRAS G12D inhibitor 1 (example 243) is an inhibitor of KRAS G12D, exhibiting an IC50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation [1].

  • Target

    Others, Kras, Ras

  • Related Pathways

    Others, MAPK, GPCR/G Protein

  • CAS Number

    2621881

  • Molecular Formula

    C33H32F2N6O2

  • Molecular Weight

    582.64

  • SMILES

    Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(cccc2c1)C#C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound