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Molfinity

KRAS G12D inhibitor 16 - CAS 2648221-12-7

KRAS G12D inhibitor 16 - CAS 2648221-12-7

SKU:MF-0146144-01

Regular price $3,542.45 USD
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  • Bioactivity

    KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant tumors including pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), and non-small cell lung carcinomas (NSCLC) .

  • Target

    Ras, Kras, Others

  • Related Pathways

    Others, MAPK, GPCR/G Protein

  • CAS Number

    2648202

  • Molecular Formula

    C32H39IN6O3

  • Molecular Weight

    682.59

  • SMILES

    C(C1(COC2=NC(=C3C(=N2)CN(CC3)C=4C5=C(C=C(O)C4)C=CC=C5I)N6CC7NC(C6)CC7)CC1)N8CCOCC8

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound