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KRAS G12D inhibitor 16 - CAS 2648221-12-7
KRAS G12D inhibitor 16 - CAS 2648221-12-7
SKU:MF-0146144-01
Regular price
$3,542.45 USD
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Sale price
$3,542.45 USD
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Product Details
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Bioactivity
KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant tumors including pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), and non-small cell lung carcinomas (NSCLC) .
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Target
Ras, Kras, Others
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Related Pathways
Others, MAPK, GPCR/G Protein
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CAS Number
2648202
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Molecular Formula
C32H39IN6O3
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Molecular Weight
682.59
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SMILES
C(C1(COC2=NC(=C3C(=N2)CN(CC3)C=4C5=C(C=C(O)C4)C=CC=C5I)N6CC7NC(C6)CC7)CC1)N8CCOCC8
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound