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KRAS inhibitor-24 - CAS 3030576-47-4

KRAS inhibitor-24 - CAS 3030576-47-4

SKU:MF-0148429-01

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  • Bioactivity

    KRAS inhibitor-24 (compound 115c), a pyrido-pyridine class KRAS inhibitor, exhibits potent activity against KRas G12V, KRas WT, and KRas G12R, with IC50 values all below 100 nM.

  • Target

    Kras, Ras

  • Related Pathways

    MAPK

  • CAS Number

    3030576-47-4

  • Molecular Formula

    C33H39ClF2N6O3

  • Molecular Weight

    641.15

  • SMILES

    C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCC(=O)NCC[C@]5(CN2CCC5)[H])[C@@]67N(C[C@H](F)C6)CCC7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound