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KRAS inhibitor-24 - CAS 3030576-47-4
KRAS inhibitor-24 - CAS 3030576-47-4
SKU:MF-0148429-01
Regular price
$2,173.55 USD
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$2,173.55 USD
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Product Details
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Bioactivity
KRAS inhibitor-24 (compound 115c), a pyrido-pyridine class KRAS inhibitor, exhibits potent activity against KRas G12V, KRas WT, and KRas G12R, with IC50 values all below 100 nM.
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Target
Kras, Ras
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Related Pathways
MAPK
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CAS Number
3030576-47-4
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Molecular Formula
C33H39ClF2N6O3
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Molecular Weight
641.15
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SMILES
C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCC(=O)NCC[C@]5(CN2CCC5)[H])[C@@]67N(C[C@H](F)C6)CCC7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound