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KRAS inhibitor-25 - CAS 3030577-05-7

KRAS inhibitor-25 - CAS 3030577-05-7

MF-0148377-01

$2,436.80 USD
$2,436.80 USD
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Product Details

  • Bioactivity

    KRAS inhibitor-25 (compound 151a), a pyrido[2,3-d]pyrimidine derivative, effectively inhibits KRas G12V, KRas WT, and KRas G12R with IC50 values all below 100 nM.

  • Target

    Kras, Ras

  • Related Pathways

    MAPK

  • CAS Number

    3030577-05-7

  • Molecular Formula

    C32H38ClF2N5O3

  • Molecular Weight

    614.13

  • SMILES

    C(OC1=NC2=C3C(=N1)C(F)=C(N=C3)C=4C(=C(Cl)C=C(O)C4)CCCCCCC5(O)CN2CCC5)[C@@]67N(C[C@H](F)C6)CCC7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound