KRAS inhibitor-31 - CAS 2920695-77-6

KRAS inhibitor-31 (compound 33), a potent agent targeting KRAS, exhibits K D (SPR) values of 0.019 nM for KRas G12D, 0.019 nM for KRas G12C, and 0.096 nM for KRas G12V, illustrating its efficacy across these variants.

Ras

MAPK, GPCR/G Protein

2920612

C33H30F3N5O4

617.62

FC=1C=2C3=C(N4[C@](COC3=NC1C=5C6=C(C=C(O)C5)C=CC(F)=C6C#C)(COCCC4)[H])N=C(OC[C@@]78N(C[C@H](F)C7)CCC8)N2

-20°C

Ice Packs

Small Compound