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KRAS inhibitor-9 - CAS 300809-71-6

KRAS inhibitor-9 - CAS 300809-71-6

MF-0018072-01

$51.11 USD
$51.11 USD
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Product Details

  • Bioactivity

    KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells

  • Target

    Kras, Ras, Apoptosis

  • Related Pathways

    Apoptosis, GPCR/G Protein, MAPK

  • CAS Number

    300732

  • Purity

    0.9994

  • Molecular Formula

    C13H9ClN2S2

  • Molecular Weight

    292.81

  • SMILES

    Nc1ccc(Sc2nc3ccccc3s2)c(Cl)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound