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KRASG12C ligand-1 - CAS 3053689-44-1
KRASG12C ligand-1 - CAS 3053689-44-1
SKU:MF-0118431-01
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Product Details
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Bioactivity
KRASG12C ligand-1 is a PROTAC target protein ligand utilized in synthesizing PROTAC YN14-H. YN14-H acts as a PROTAC degrader targeting KRASG12C, exhibiting antitumor activity.
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Target
Ligands for Target Protein for PROTAC, Ras
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Related Pathways
MAPK, PROTAC
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CAS Number
3053644
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Molecular Formula
C36H41F2N7O3
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Molecular Weight
657.75
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SMILES
O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(OCC5CCNCC5)C=CC=C4F)C6=C(C(C)C)N=CC=C6C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC