KRH-3955 hydrochloride - CAS 2253744-59-9

KRH-3955 hydrochloride is a CXCR4 antagonist with oral bioavailability. It effectively inhibits the binding of SDF-1α to CXCR4, exhibiting an IC 50 of 0.61 nM. Additionally, KRH-3955 hydrochloride displays high potency and selectivity as an inhibitor of X4 HIV-1, with an EC 50 ranging from 0.3 to 1.0 nM.

Others, CXCR, HIV Protease

Microbiology/Virology, Others, Immunology/Inflammation, Proteases/Proteasome, Autophagy, GPCR/G Protein

2253744-59-9

C28H48Cl3N7

589.09

Cl.Cl.Cl.CCCN(CCC)CCCCN(C)Cc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1

-20°C

Ice Packs

Small Compound