KRH102053 - CAS 1353254-53-1

KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.

Others

Others

1353200

C25H34N2O5S

474.61

O(C)C1C=2C(OC(C)(C)C1OC(C(CCSC)N)=O)=CC=C(NCC3=CC=C(OC)C=C3)C2

-20°C

Ice Packs

Small Compound