KRIBB3 - CAS 129414-88-6

KRIBB3 is novel and potent microtubule inhibitor with potential anticancer activity. KRIBB3 has anti-migratory and anti-invasive activities in MDA-MB-231 cells. KRIBB3 inhibits tumor cell migration and invasion by blocking protein kinase C-dependent phosphorylation of Hsp27 through its direct binding to Hsp27.

Microtubule Associated, Apoptosis, Others

Apoptosis, Cytoskeletal Signaling, Others

129320

C19H19NO4

325.36

OC=1C(C2=C(C=NO2)C3=CC=C(OC)C=C3)=CC(CC)=C(OC)C1

-20°C

Ice Packs

Small Compound