KS-133 - CAS 2724212-01-3

KS-133 is a selective and potent antagonist of the vasoactive intestinal peptide receptor 2 (VIPR2), exhibiting IC50 values of 24.8 nM in intracellular calcium influx assays and 500 nM in cAMP assays. This compound plays a crucial role in research on schizophrenia.

2724212-01-3

C75H111N15O17S2

1558.9

O=C1[C@]2(N(C(=O)[C@@H](NC(C)=O)CSSC[C@]3(C(=O)N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(N)=O)=O)CC(C)C)=O)CC(=O)NCCCC[C@](NC(=O)[C@]4(N(C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC5=CC=C(O)C=C5)NC(=O)[C@]6(N1CCC6)[H])CCC4)[H])(C(=O)N[C@@H](CC7=CC=C(O)C=C7)C(=O)N[C@@H](CC(C)C)C(=O)N3)[H])[H])CCC2)[H]

-20°C

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Small Compound